CASCADE II: A quantitive study in early COPD, using a cluster analysis, to establish if prospective, individualised, medical intervention alters projected clinical course

WessexRespiratory
Start Date: 1 Jul 2015 End Date: 31 Jan 2017

A quantitative study in early Chronic Obstructive Pulmonary Disease, using a cluster analysis, to establish if prospective, individualised, medical intervention alters projected clinical course. CASCADE II

The background

People with COPD, with a past history of smoking, are at higher risk of other medical problems such as heart disease and stroke. Being breathless and having multiple physical health problems can also lead to mental health problems such as anxiety and depression. This means it can be challenging to provide this group of people enough time to fully assess and treat all their problems, particularly due to current pressure on the length of GP appointment times. Whilst COPD is treatable, it is not curable, and emphasis on early diagnosis and intervention is key.

The solution 

We aim to identify those COPD patients who currently have milder disease and to investigate whether a detailed, medical assessment which has time to assess all aspects of their care will improve their lung health and general wellbeing. Using COPD patients deemed ‘low risk’ by DOSE score, this cluster randomised controlled interventional study will establish whether intervention in the form of a prospective, in depth, medical assessment and individualised optimisation of care will alter their respiratory health status and clinical outcomes.

Expected outcome

We are hoping to prove that a complex intervention to optimise clinical and supportive care in early stage COPD patients will improve health outcomes and be cost effective. 

Contact 
Dr Lucy Rigge
https://www.clahrc-wessex.nihr.ac.uk/projects/71/dr-lucy-rigge