Does total joint arthroplasty of the hip and knee reduce the risk for serious cardiovascular events in patients with moderate-severe osteoarthritis?

West MidlandsDiagnostics & Stratified Medicine, Generic Health Relevance, Musculoskeletal
Start Date: 1 Jan 2014


It has been observed that patients with arthritis who have a hip or knee joint replacement seem to have less heart disease than similar patients who do not have hip or knee joint replacement. It is unclear whether this is because subtly healthier patients are selected to have joint replacement or because joint replacement improves their general health.

Aim of the study

This study will try to work out if joint replacement really did result in fewer of them having heart disease after surgery.


The researchers will analyse records of arthritis patients who had hip or knee joint replacement compared to arthritis patients of the same age and sex who did not.

Prof Tom Marshall