Impact of Visual Impairment after Stroke. The IVIS Study

North West CoastStroke
Start Date: 1 Jan 2015


Eye movement disorders following stroke are typically due to damage to the neural pathways that control eye movements. Up to 68% of stroke survivors with visual symptoms have eye movement disorders and these impact by causing a range of difficulties including inability to maintain normal ocular alignment or move the eyes appropriately. 

This systematic review of interventions for eye movement disorders in patients with acquired brain injury will seek to synthesise the current evidence base, to guide current practice and aid in the development of well-designed randomised controlled trials. 


The purpose of the clinical observation study is to firstly determine prevalence of visual impairment by systematically evaluating all (consecutive admissions) stroke survivors within three geographically separate stroke units using validated orthoptic measures.

Three distinct units (hyper-acute stroke unit plus district general stroke unit) will enable representation to be drawn from different geographical areas with different demographics to ensure as representative a sample of stroke survivors as possible.

Secondly, the natural history and long-term outcome for visual impairment due to stroke will be determined by longitudinal follow-up of stroke survivors with objective diagnosis of visual impairment.


Dr Fiona Rowe